Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438828 | 0.94 | KMT2A (0.41) | SMN1; SMN2LMNAKMT2ACYP2C9ALDH1A1 | |
| SCHEMBL8670315 | 0.87 | MAPT (0.33) | SMN1; SMN2LMNAKMT2AMAPTNPC1 | |
| SCHEMBL8668979 | 0.85 | MEN1 (0.36) | SMN1; SMN2LMNAKMT2AALDH1A1HPGD | |
| SCHEMBL8668966 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAKMT2ACYP2C9ALDH1A1 | |
| SCHEMBL8436458 | 0.80 | MAPT (0.48) | LMNAKMT2ACYP2C9ALDH1A1HPGD | |
| SCHEMBL8442772 | 0.79 | HTR1D (0.41) | SMN1; SMN2LMNAKMT2AACHEGAA | |
| SCHEMBL8672637 | 0.78 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAKMT2ACYP2C9ALDH1A1 | |
| SCHEMBL8442999 | 0.78 | HTR1D (0.35) | SMN1; SMN2LMNAKMT2AALDH1A1NPY1R | |
| SCHEMBL8672844 | 0.77 | MAPT (0.30) | MAPTPTGS1 | |
| SCHEMBL8440207 | 0.77 | NPSR1 (0.36) | KMT2AALDH1A1MAPTNPY1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840910-A | Pyridine derivatives having anti-ulcerative activity | ESAI CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |