Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670315 | 0.85 | MAPT (0.33) | MAPT | |
| SCHEMBL8668979 | 0.83 | MEN1 (0.36) | MAPT | |
| SCHEMBL8670335 | 0.81 | CYP2C9 (0.36) | MAPTPTGS1 | |
| SCHEMBL8438828 | 0.80 | KMT2A (0.41) | MAPTPTGS1 | |
| SCHEMBL8672847 | 0.80 | MAPT (0.33) | MAPTPTGS1PTGS2 | |
| SCHEMBL8436458 | 0.78 | MAPT (0.48) | MAPT | |
| SCHEMBL8672636 | 0.77 | SMN1; SMN2 (0.37) | MAPTPTGS1 | |
| SCHEMBL8442772 | 0.75 | HTR1D (0.41) | — | |
| SCHEMBL8440207 | 0.74 | NPSR1 (0.36) | MAPT | |
| SCHEMBL8438635 | 0.73 | POLB (0.43) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840910-A | Pyridine derivatives having anti-ulcerative activity | ESAI CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |