Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 12/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TRHR | P34981 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2190498 | 0.86 | CNR1 (0.41) | HDAC3HDAC11HDAC6HDAC1HDAC10 | |
| SCHEMBL13113739 | 0.82 | HDAC3 (0.42) | HDAC3HDAC11HDAC6HDAC1HDAC10 | |
| SCHEMBL23300538 | 0.81 | HDAC3 (0.48) | HDAC3HDAC11HDAC6HDAC1HDAC10 | |
| SCHEMBL23300537 | 0.81 | HDAC3 (0.48) | HDAC3HDAC11HDAC6HDAC1HDAC10 | |
| SCHEMBL29776748 | 0.81 | HDAC3 (0.48) | HDAC3HDAC11HDAC6HDAC1HDAC10 | |
| SCHEMBL8669058 | 0.79 | POLB (0.39) | HDAC3HDAC11HDAC6HDAC1HDAC10 | |
| SCHEMBL1607473 | 0.78 | POLB (0.38) | HDAC3HDAC11HDAC6HDAC1HDAC10 | |
| SCHEMBL10819021 | 0.74 | CTSB (0.46) | — | |
| SCHEMBL10533944 | 0.74 | CTSB (0.46) | — | |
| SCHEMBL10335267 | 0.74 | CTSC (0.52) | HDAC3HDAC11HDAC6HDAC1HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301639-A2 | Analogues of the bradykinin potentiating peptide BPP 5a and methods for their preparation | ENI-Ente Nazionale Idrocarburi (IT) | 1989-02-01 | — | — | EP | disclosed |
| EP-0190597-A2 | Retro-inverso analogs of the bradykinin potentiating peptide bpp 5a | SCLAVO S.p.A. (IT) | 1986-08-13 | — | — | EP | disclosed |