Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10580958 | 0.86 | HDAC3 (0.40) | CNR1DAGLAHDAC3HDAC11HDAC6 | |
| SCHEMBL1607473 | 0.82 | POLB (0.38) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL11733472 | 0.81 | HDAC3 (0.47) | CNR1DAGLAHDAC3HDAC11HDAC6 | |
| SCHEMBL8669058 | 0.80 | POLB (0.39) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL11740264 | 0.80 | HDAC3 (0.46) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL10335267 | 0.75 | CTSC (0.52) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL9000850 | 0.74 | TSHR (0.43) | CNR1DAGLAPOLBSMN1; SMN2MEN1 | |
| SCHEMBL11738552 | 0.74 | PRCP (0.53) | SMN1; SMN2 | |
| SCHEMBL9350324 | 0.73 | CNR1 (0.51) | CNR1DAGLAHDAC3HDAC11HDAC6 | |
| SCHEMBL25039712 | 0.73 | POLB (0.46) | HDAC3HDAC11HDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682153-B2 | Polymer conjugates of therapeutic peptides | NEKTAR THERAPEUTICS (US) | 2017-06-20 | — | — | US | disclosed |
| US-20160022828-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS | 2016-01-28 | — | — | US | disclosed |
| US-20110171312-A1 | MODIFIED THERAPEUTIC PEPTIDES, METHODS OF THEIR PREPARATION AND USE | NEKTAR THERAPEUTICS (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022828-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | CNR1 4064/4885DAGLA 4536/4885HDAC3 3446/4885 |
| US-20110171312-A1 | MODIFIED THERAPEUTIC PEPTIDES, METHODS OF THEIR PREPARATION AND USE | DNPEP, VIP, PTMS | CNR1 4163/4885DAGLA 4543/4885HDAC3 3341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.