Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11036917 | 0.84 | ALDH1A1 (0.50) | ALDH1A1NPSR1MAPTTDP1CTSD | |
| SCHEMBL3378050 | 0.83 | ALDH1A1 (0.53) | ALDH1A1NPSR1MAPTTDP1CTSD | |
| SCHEMBL8669115 | 0.80 | PLAU (0.46) | ALDH1A1MAPTTDP1CTSDKDM4E | |
| SCHEMBL27490350 | 0.79 | CTSD (0.53) | ALDH1A1NPSR1MAPTTDP1CTSD | |
| SCHEMBL6048773 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TDP1CTSDKMT2ASMN1; SMN2 | |
| SCHEMBL30704256 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TDP1CTSDKMT2ASMN1; SMN2 | |
| SCHEMBL28783806 | 0.79 | ALDH1A1 (0.46) | ALDH1A1NPSR1MAPTTDP1CTSD | |
| SCHEMBL30500285 | 0.79 | ALDH1A1 (0.46) | ALDH1A1NPSR1MAPTTDP1KDM4E | |
| SCHEMBL9034389 | 0.79 | CTSD (0.44) | ALDH1A1MAPTTDP1CTSDKDM4E | |
| SCHEMBL8470246 | 0.76 | CES2 (0.45) | ALDH1A1MAPTTDP1CTSDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324988-B1 | 4-CHLOR-3-SULFAMOYL BENZOIC ACID HYDRAZIDES, PROCESS FOR THEIR PREPARATION, MEDICINES CONTAINING THEM AND USE OF THESE COMPOUNDS IN THE PREPARATION OF DIURETIC AND SALT REDUCING ACTIVITY MEDICINES | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1992-04-29 | — | — | EP | disclosed |
| EP-0324988-A1 | 4-Chlor-3-sulfamoyl benzoic acid hydrazides, process for their preparation, medicines containing them and use of these compounds in the preparation of diuretic and salt reducing activity medicines | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1989-07-26 | — | — | EP | disclosed |