Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 3/20 | 0.38 |
| ▸ | CCKAR | P32238 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672710 | 0.92 | PDE4D (0.46) | LMNAMAPTOPRK1TP53CCKBR | |
| SCHEMBL8669230 | 0.90 | HTR2B (0.45) | LMNAMAPTOPRK1KCNH2TP53 | |
| SCHEMBL8801708 | 0.82 | FNTA (0.49) | LMNAPOLBMAPTTP53CCKBR | |
| SCHEMBL8667954 | 0.81 | CCKBR (0.48) | KCNH2TP53CCKBRCCKAR | |
| SCHEMBL8674133 | 0.81 | CCKBR (0.48) | KCNH2TP53CCKBRCCKAR | |
| SCHEMBL8669346 | 0.78 | HTR2B (0.41) | LMNAMAPTOPRK1KCNH2TP53 | |
| SCHEMBL8670231 | 0.77 | OPRK1 (0.57) | LMNAOPRK1KCNH2CCKBRCCKAR | |
| SCHEMBL8670227 | 0.77 | HTR2B (0.49) | LMNAMAPTOPRK1KCNH2TP53 | |
| SCHEMBL8674051 | 0.76 | HTR2B (0.42) | LMNAPOLBMAPTOPRK1KCNH2 | |
| SCHEMBL8674481 | 0.76 | HTR2B (0.45) | LMNAMAPTOPRK1KCNH2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |