Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 4/20 | 0.42 |
| ▸ | CCKAR | P32238 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672710 | 0.91 | PDE4D (0.46) | HTR2BPDE4DOPRK1LMNAPDE3A | |
| SCHEMBL8674133 | 0.90 | CCKBR (0.48) | CCKBRCCKARFNTAFNTBTP53 | |
| SCHEMBL8667954 | 0.90 | CCKBR (0.48) | CCKBRCCKARFNTAFNTBTP53 | |
| SCHEMBL8669399 | 0.90 | LMNA (0.41) | OPRK1LMNACCKBRCCKARMAPT | |
| SCHEMBL8670231 | 0.88 | OPRK1 (0.57) | HTR2BPDE4DOPRK1LMNAPDE3A | |
| SCHEMBL8669346 | 0.88 | HTR2B (0.41) | HTR2BPDE4DOPRK1LMNAPDE3A | |
| SCHEMBL8670227 | 0.87 | HTR2B (0.49) | HTR2BPDE4DOPRK1LMNAPDE3A | |
| SCHEMBL8674481 | 0.84 | HTR2B (0.45) | HTR2BPDE4DOPRK1LMNAPDE3A | |
| SCHEMBL8670552 | 0.84 | HTR2B (0.45) | HTR2BPDE4DOPRK1LMNAPDE3A | |
| SCHEMBL8801536 | 0.84 | OXTR (0.45) | HTR2BPDE4DCCKBRNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |