Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 5/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5305951 | 0.81 | AKR1C2 (0.49) | AKR1C2TRPV1PDGFRBFGFR1KDR | |
| SCHEMBL4562595 | 0.78 | AKR1C2 (0.48) | AKR1C2TRPV1PDGFRBFGFR1KDR | |
| SCHEMBL11021014 | 0.75 | TRPV1 (0.46) | AKR1C2TRPV1PDGFRBFGFR1KDR | |
| SCHEMBL8796396 | 0.72 | TRPV1 (0.46) | AKR1C2TRPV1PDGFRBFGFR1KDR | |
| SCHEMBL8978361 | 0.70 | TRPV1 (0.42) | AKR1C2TRPV1PDGFRBFGFR1KDR | |
| SCHEMBL8978296 | 0.70 | PDGFRB (0.42) | AKR1C2TRPV1PDGFRBFGFR1KDR | |
| SCHEMBL25260242 | 0.69 | ALDH1A1 (0.58) | AKR1C2PDGFRBFGFR1KDRMTNR1A | |
| SCHEMBL10637946 | 0.69 | PIKFYVE (0.42) | AKR1C2TRPV1PDGFRBFGFR1KDR | |
| SCHEMBL10634943 | 0.69 | TRPV1 (0.43) | AKR1C2TRPV1PDGFRBFGFR1KDR | |
| SCHEMBL11832981 | 0.69 | TRPV1 (0.51) | AKR1C2TRPV1PDGFRBFGFR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750558-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | disclosed |