Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.44 |
| ▸ | HTR3B | O95264 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30945574 | 0.78 | LMNA (0.44) | ALDH1A1KDM4EHRH3HTR3AHTR1A | |
| SCHEMBL20571087 | 0.78 | CYP2A6 (0.44) | ALDH1A1KDM4ECYP3A4HTTNPC1 | |
| SCHEMBL10772513 | 0.77 | NPC1 (0.45) | ALDH1A1KDM4EHTR3AHTTHRH4 | |
| SCHEMBL28303005 | 0.77 | CYP2A6 (0.47) | ALDH1A1KDM4ECYP1A2HTTNPC1 | |
| SCHEMBL8342753 | 0.73 | GAA (0.49) | ALDH1A1KDM4ECYP1A2TDP1CYP3A4 | |
| SCHEMBL30344655 | 0.73 | ALDH1A1 (0.48) | ALDH1A1KDM4EHRH3CYP1A2HTR3E | |
| SCHEMBL3806773 | 0.73 | ALDH1A1 (0.48) | ALDH1A1KDM4EHRH3CYP1A2HTR3E | |
| SCHEMBL28333293 | 0.72 | HTR3A (0.46) | ALDH1A1KDM4ECYP1A2HTR3AHRH4 | |
| SCHEMBL31556855 | 0.72 | KDM4E (0.45) | ALDH1A1KDM4ECYP1A2HTTSMN1; SMN2 | |
| SCHEMBL21623963 | 0.72 | KDM4E (0.45) | ALDH1A1KDM4ECYP1A2HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830903-A | ANTIULCER AGENTS | ALKALOIDA CHEMICAL CO., LTD. (HU) | 1998-11-03 | — | — | US | disclosed |