Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669685 | 0.95 | NPSR1 (0.42) | NPSR1CHRM1UTS2RCARM1PRMT6 | |
| SCHEMBL8502237 | 0.92 | NPSR1 (0.38) | NPSR1CHRM1UTS2RHPGDDRD2 | |
| SCHEMBL8665880 | 0.87 | UTS2R (0.39) | NPSR1CHRM1UTS2RCARM1PRMT6 | |
| SCHEMBL8666092 | 0.84 | UTS2R (0.39) | NPSR1CHRM1UTS2RCARM1PRMT6 | |
| SCHEMBL8501233 | 0.83 | NPSR1 (0.36) | NPSR1CHRM1UTS2RHPGDDRD2 | |
| SCHEMBL8480927 | 0.82 | NPSR1 (0.41) | NPSR1HPGDGAADRD2HTR1A | |
| SCHEMBL8485533 | 0.82 | NPSR1 (0.42) | NPSR1UTS2RCARM1PRMT6DRD2 | |
| SCHEMBL8480408 | 0.81 | TMEM97 (0.38) | NPSR1HPGDGAAHTR2AALDH1A1 | |
| SCHEMBL8501048 | 0.81 | NPSR1 (0.35) | NPSR1CHRM1UTS2RHPGDHTR2A | |
| SCHEMBL8484454 | 0.79 | NPSR1 (0.42) | NPSR1UTS2RCARM1PRMT6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |