Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668130 | 0.79 | RAB9A (0.46) | RAB9ASLC6A3SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL4938098 | 0.79 | SLC6A3 (1.00) | SLC6A3SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL8667307 | 0.78 | RAB9A (0.45) | RAB9ASLC6A3SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL27098440 | 0.76 | SLC6A3 (0.69) | RAB9ASLC6A3SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL27098435 | 0.76 | SLC6A3 (0.69) | RAB9ASLC6A3SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL4936204 | 0.76 | SLC6A3 (1.00) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9037624 | 0.75 | SLC6A3 (0.68) | RAB9ASLC6A3SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL5505886 | 0.75 | HTR1A (0.69) | RAB9ASLC6A3SLC6A4ALDH1A1KMT2A | |
| SCHEMBL2552830 | 0.75 | SLC6A3 (0.68) | RAB9ASLC6A3SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL27098434 | 0.75 | SLC6A3 (0.81) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770740-A | TREATING DEPRESSION AND OBSESSIVE COMPULSIVE DISORDERS | HOECHST MARION ROUSSEL, INC. (US) | 1998-06-23 | — | — | US | disclosed |
| US-5696142-A | TREATING DEPRESSION, OBSESSIVE COMPULSIVE DISORDERS | HOECHST MARION ROUSSEL, INC. (US) | 1997-12-09 | — | — | US | disclosed |
| US-5686447-A | ANTIDEPRESSANTS, OBSESSIVE COMPULSIVE DISORDERS | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5686483-A | TREATING DEPRESSION AND OBSESSIVE COMPULSIVE DISORDERS | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5686446-A | ANTIDEPRESSANTS, OBSESSIVE COMPULSIVE DISORDERS | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5684021-A | Aminoalkyloximes for treating depression and affective disorders | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-04 | — | — | US | disclosed |