Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669805 | 0.98 | GRM4 (0.38) | LMNASMN1; SMN2TSHRALOX15HTT | |
| SCHEMBL8435845 | 0.80 | CYP2C9 (0.37) | LMNATSHRHTTMAPTHPGD | |
| SCHEMBL630973 | 0.77 | POLB (0.43) | LMNASMN1; SMN2TSHRALOX15HTT | |
| SCHEMBL27561186 | 0.76 | POLB (0.42) | LMNASMN1; SMN2TSHRALOX15HTT | |
| SCHEMBL5943999 | 0.75 | MAPT (0.45) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL5448791 | 0.72 | MAPT (0.40) | LMNASMN1; SMN2TSHRHTTMEN1 | |
| SCHEMBL8503824 | 0.72 | NOS1 (0.47) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL636638 | 0.70 | CYP11B1 (0.50) | LMNASMN1; SMN2TSHRALOX15HTT | |
| SCHEMBL8503831 | 0.70 | MAPT (0.39) | LMNASMN1; SMN2TSHRHTTKMT2A | |
| SCHEMBL8502624 | 0.70 | NOS1 (0.47) | LMNASMN1; SMN2HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840910-A | Pyridine derivatives having anti-ulcerative activity | ESAI CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |