Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | IDE | P14735 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5943999 | 0.94 | MAPT (0.45) | MAPTLMNAKMT2AALDH1A1CYP2C9 | |
| SCHEMBL3665713 | 0.84 | MAPT (0.52) | MAPTLMNAKMT2AALDH1A1CYP2C9 | |
| SCHEMBL8501869 | 0.82 | ALDH1A1 (0.34) | MAPTLMNAKMT2AALDH1A1CYP2C9 | |
| SCHEMBL5984224 | 0.80 | RAB9A (0.41) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5634925 | 0.76 | MAPT (0.34) | MAPT | |
| SCHEMBL30065339 | 0.74 | AGXT (0.42) | MAPTLMNAKMT2AALDH1A1CYP2C9 | |
| SCHEMBL5988718 | 0.74 | AGXT (0.42) | MAPTLMNAKMT2AALDH1A1CYP2C9 | |
| SCHEMBL8502864 | 0.73 | KMT2A (0.46) | MAPTLMNAKMT2AALDH1A1CYP2C9 | |
| SCHEMBL8669805 | 0.72 | GRM4 (0.38) | MAPTLMNAKMT2AALDH1A1HPGD | |
| SCHEMBL8669942 | 0.72 | LMNA (0.40) | MAPTLMNAKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007129328-A2 | PROCESS FOR PREPARING 2-[PYRIDINYL]SULFINYL-SUBSTITUTED BENZIMIDAZOLES | CADILA HEALTHCARE LIMITED (IN) | 2007-11-15 | — | — | WO | disclosed |