Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27561186 | 0.99 | POLB (0.42) | POLBMKNK1MKNK2TDP1LMNA | |
| SCHEMBL636638 | 0.80 | CYP11B1 (0.50) | TDP1LMNASMN1; SMN2ALDH1A1TNF | |
| SCHEMBL8669942 | 0.77 | LMNA (0.40) | MKNK1MKNK2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8435845 | 0.77 | CYP2C9 (0.37) | LMNAHTTTSHR | |
| SCHEMBL8669805 | 0.77 | GRM4 (0.38) | MKNK1MKNK2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9560914 | 0.76 | TDP1 (0.46) | POLBTDP1LMNASMN1; SMN2TNF | |
| SCHEMBL10587534 | 0.75 | POLB (0.39) | POLBTDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3335253 | 0.74 | POLB (0.46) | POLBMKNK1MKNK2TDP1LMNA | |
| SCHEMBL1618548 | 0.73 | TDP1 (0.48) | POLBTDP1LMNASMN1; SMN2TNF | |
| SCHEMBL9236926 | 0.73 | TDP1 (0.42) | POLBTDP1LMNASMN1; SMN2TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 419 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419092-B1 | PHARMACEUTICAL COMPOSITION FOR TREATING DERMATOLOGICAL AUTOIMMUNE DISEASES | AGON PHARMA GMBH (DE) | 2016-05-04 | — | — | EP | claimed |
| US-8465767-B2 | Mixture with tablet distegrant; sustained release; embedding water soluble particle in plastic membrane coating ; stomach disorders | TAKEDA GMBH (DE) | 2013-06-18 | — | — | US | claimed |
| EP-2419092-A2 | PHARMACEUTICAL COMPOSITION FOR TREATING DERMATOLOGICAL AUTOIMMUNE DISEASES | Agon Pharma GmbH (DE) | 2012-02-22 | — | — | EP | claimed |
| WO-2010119102-A2 | PHARMACEUTICAL COMPOSITION FOR TREATING DERMATOLOGICAL AUTOIMMUNE DISEASES | AGON PHARMA GMBH (DE) | 2010-10-21 | — | — | WO | claimed |
| US-7785630-B2 | Preparation and administration form comprising an acid-labile active compound | NYCOMED GMBH (DE) | 2010-08-31 | — | — | US | claimed |
| WO-2009147178-A2 | NOVEL MEDICAL USE OF SUBSTITUTED PYRIDIN-2-YLMETHYLSULPHINYL-1H-BENZIMIDAZOLES | NYCOMED GMBH (DE) | 2009-12-10 | — | — | WO | claimed |
| EP-1802584-B1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED SULFOXIDES | RANBAXY LAB LTD (IN) | 2009-09-16 | — | — | EP | claimed |
| US-20090068261-A1 | ORAL RAPID RELEASE PHARMACEUTICAL FORMULATION FOR PYRIDYLMETHYLSULFINYL-BENZIMIDAZOLES | MEPHA SCHWEIZ AG (CH) | 2009-03-12 | — | — | US | claimed |
| CN-100457104-C | Alkaline salts of proton pump inhibitors | ALTANA PHARMA AG (DE) | 2009-02-04 | — | — | CN | claimed |
| EP-2012754-A1 | ORAL RAPID RELEASE PHARMACEUTICAL FORMULATION FOR PYRIDYLMETHYLSULFINYL-BENZIMIDAZOLES | Mepha AG (CH) | 2009-01-14 | — | — | EP | claimed |
| WO-2003089408-A2 | OPTICALLY ACTIVE SUBSTITUTED PYRIDINYLMETHYL-SULPHINYL-BENZIMIDAZOLE AND SALTS | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2003-10-30 | — | — | WO | claimed |
| US-6607742-B2 | Suppository composition which is a spray-dried suspension of an acid-labile proton pump inhibitor in a solvent solution of a sterol and polymer | ALTANA PHARMA AG (DE) | 2003-08-19 | — | — | US | claimed |
| WO-2003059393-A1 | PANTOPRAZOLE CYCLODEXTRIN INCLUSION COMPLEXES | ALTANA PHARMA AG (DE) | 2003-07-24 | — | — | WO | claimed |
| US-20020188008-A1 | Novel salt form of pantoprazole | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH | 2002-12-12 | — | — | US | claimed |
| US-20020090397-A1 | Novel suppository form comprising an acid-labile active compound | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH | 2002-07-11 | — | — | US | claimed |
| EP-1105105-A1 | ORAL ADMINISTRATION FORM FOR PYRIDIN-2-YLMETHYLSULFINYL-1H-BENZIMIDAZOLES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-06-13 | — | — | EP | claimed |
| WO-2000009092-A1 | ORAL ADMINISTRATION FORM FOR PYRIDIN-2-YLMETHYLSULFINYL-1H-BENZIMIDAZOLES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-02-24 | — | — | WO | claimed |
| WO-1999027917-A1 | MEDICAMENT PREPARATION IN THE FORM OF A TABLET OR PELLET FOR ACID-LABILE ACTIVE SUBSTANCES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-06-10 | — | — | WO | claimed |
| EP-0279149-B1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Aktiebolaget Hässle (SE) | 1992-12-30 | — | — | EP | claimed |
| EP-0233284-B1 | PHARMACOLOGICAL COMPOUNDS | Aktiebolaget Hässle (SE) | 1992-08-19 | — | — | EP | claimed |