SCHEMBL8669976

SCHEMBL8669976

Cc1ccc(S(=O)(=O)C(C)(C)C(=O)c2ccc(Sc3ccc(C(=O)C(C)(C)S(=O)(=O)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.41
LMNA P02545 3/20 0.41
HPGD P15428 3/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM4E B2RXH2 1/20 0.40
APEX1 P27695 1/20 0.40
CA2 P00918 1/20 0.39
ALDH1A1 P00352 4/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CYP2C19 P33261 1/20 0.39
PPARG P37231 1/20 0.39
NCOA2 Q15596 1/20 0.39
NCOA1 Q15788 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
GFER P55789 1/20 0.38
MLYCD O95822 1/20 0.37
PTPN1 P18031 1/20 0.37
BCL2 P10415 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12757096 0.96 LMNA (0.44) DNMT1LMNAHPGDL3MBTL1KDM4E
SCHEMBL3425319 0.96 DNMT1 (0.38) DNMT1LMNAHPGDL3MBTL1KDM4E
SCHEMBL12757093 0.91 LMNA (0.40) DNMT1LMNAHPGDKDM4EAPEX1
SCHEMBL195111 0.91 AKR1C3 (0.41) LMNAHPGDKDM4EAPEX1CA2
SCHEMBL6551010 0.91 LMNA (0.46) LMNAHPGDCA2ALDH1A1MEN1
SCHEMBL12757102 0.90 LMNA (0.39) DNMT1LMNAHPGDL3MBTL1KDM4E
SCHEMBL12757095 0.90 KMT2A (0.42) LMNAL3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL5272382 0.90 ALDH1A1 (0.47) DNMT1LMNACA2ALDH1A1MEN1
SCHEMBL23003257 0.89 RECQL (0.39) LMNAHPGDKDM4EAPEX1ALDH1A1
SCHEMBL12757090 0.88 ALDH1A1 (0.44) LMNAHPGDKDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850253-A1 BETAKETOSULFONIC DERIVATIVES SUITABLE TO THE USE AS POLYMERIZATION PHOTOINITIATORS AND PHOTOPOLYMERIZABLE SYSTEMS CONTAINING THE SAME LAMBERTI S.p.A. (IT) 1998-07-01 EP disclosed
WO-1997010270-A1 BETAKETOSULFONIC DERIVATIVES SUITABLE TO THE USE AS POLYMERIZATION PHOTOINITIATORS AND PHOTOPOLYMERIZABLE SYSTEMS CONTAINING THE SAME LAMBERTI S.P.A. (IT) 1997-03-20 WO disclosed