Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669976 | 0.96 | DNMT1 (0.41) | DNMT1LMNAKDM4EAPEX1HPGD | |
| SCHEMBL12757096 | 0.92 | LMNA (0.44) | DNMT1LMNAKDM4EAPEX1HPGD | |
| SCHEMBL12757101 | 0.92 | CA1 (0.43) | LMNAKDM4EAPEX1HPGDMEN1 | |
| SCHEMBL195111 | 0.87 | AKR1C3 (0.41) | LMNAKDM4EAPEX1HPGDMEN1 | |
| SCHEMBL12757093 | 0.87 | LMNA (0.40) | DNMT1LMNAKDM4EAPEX1HPGD | |
| SCHEMBL6551010 | 0.87 | LMNA (0.46) | LMNAHPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL12757095 | 0.86 | KMT2A (0.42) | LMNAL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL12757102 | 0.86 | LMNA (0.39) | DNMT1LMNAKDM4EAPEX1HPGD | |
| SCHEMBL5272382 | 0.86 | ALDH1A1 (0.47) | DNMT1LMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL23003257 | 0.85 | RECQL (0.39) | LMNAKDM4EAPEX1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687220-B2 | Oxime derivatives and use thereof as latent acids | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-03-30 | — | — | US | disclosed |
| US-20080085458-A1 | Oxime Derivatives And Use Thereof As Latent Acids | CIBA SPECIALTY CHEMICALS CORPORATION | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085458-A1 | Oxime Derivatives And Use Thereof As Latent Acids | ARSA, CYP2S1, QSOX1 | DNMT1 3737/4885LMNA 421/4885KDM4E 2443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.