Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | IARS1 | P41252 | 5/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429303 | 0.83 | ALB (0.40) | ALBLMNANT5EPRMT5WDR77 | |
| SCHEMBL8670080 | 0.82 | IARS1 (0.45) | LMNAIARS1 | |
| SCHEMBL1740045 | 0.80 | ALB (0.45) | ALBLMNANT5EPRMT5WDR77 | |
| SCHEMBL331945 | 0.74 | LMNA (0.56) | ALBLMNATHRBMTORMDM2 | |
| SCHEMBL15119375 | 0.74 | LMNA (0.56) | ALBLMNATHRBMTORMDM2 | |
| SCHEMBL13621266 | 0.74 | LMNA (0.56) | ALBLMNATHRBMTORMDM2 | |
| SCHEMBL331944 | 0.74 | LMNA (0.56) | ALBLMNATHRBMTORMDM2 | |
| SCHEMBL2467656 | 0.74 | LMNA (0.56) | ALBLMNATHRBMTORMDM2 | |
| SCHEMBL10041945 | 0.74 | LMNA (0.56) | ALBLMNATHRBMTORMDM2 | |
| SCHEMBL12029778 | 0.74 | LMNA (0.56) | ALBLMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783689-A | Antibacterial and antifungal nucleosides | UNIVERSITY OF NOTRE DAME (US) | 1998-07-21 | — | — | US | disclosed |