Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9859567 | 0.75 | PDE3B (0.42) | PGRKDM4EHTTALDH1A1 | |
| SCHEMBL26115222 | 0.71 | ALDH1A1 (0.34) | PGRKDM4EHTTNPSR1MEN1 | |
| SCHEMBL9392792 | 0.70 | HTT (0.49) | KDM4EPOLBHTTNPSR1MEN1 | |
| SCHEMBL9859798 | 0.69 | SLC6A3 (0.41) | HTTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL7815498 | 0.67 | MEN1 (0.42) | PTGS2PTGS1MEN1KMT2A | |
| SCHEMBL761385 | 0.67 | ALDH1A1 (0.52) | PGRKDM4EPOLBHTTNPSR1 | |
| SCHEMBL4850775 | 0.66 | ALDH1A1 (0.36) | KDM4EHTTALDH1A1 | |
| SCHEMBL9320540 | 0.65 | HTT (0.35) | KDM4EHTTNPSR1ALDH1A1 | |
| SCHEMBL4855252 | 0.64 | BRD4 (0.33) | PTGS2PTGS1KDM4EPOLBHTT | |
| SCHEMBL9590361 | 0.64 | KDM5B (0.41) | HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798311-A | INSECTICIDES | ROHM AND HAAS COMPANY (US) | 1998-08-25 | — | — | US | disclosed |
| EP-0466408-A1 | N-aryl-3-aryl-4-substituted-4,5-dihydro-1H-pyrazole-1-carboxamides and processes for their production | ROHM AND HAAS COMPANY (US) | 1992-01-15 | — | — | EP | disclosed |