Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13647207 | 0.78 | LMNA (0.58) | RAB9ASMN1; SMN2NPC1NOTUMKDM4E | |
| SCHEMBL30844256 | 0.78 | LMNA (0.58) | RAB9ASMN1; SMN2NPC1NOTUMKDM4E | |
| SCHEMBL7868084 | 0.75 | NAMPT (0.58) | RAB9AFFAR2HTTSMN1; SMN2NPC1 | |
| SCHEMBL14943436 | 0.74 | RAB9A (0.55) | FPR2RAB9AHTTSMN1; SMN2NPC1 | |
| SCHEMBL12401164 | 0.74 | RAB9A (0.54) | FPR2RAB9AHTTSMN1; SMN2NPC1 | |
| SCHEMBL6951443 | 0.74 | ADAM17 (0.61) | FPR2ADAM17SMN1; SMN2 | |
| SCHEMBL12468403 | 0.74 | RAB9A (0.52) | FPR2RAB9AHTTSMN1; SMN2NPC1 | |
| SCHEMBL7030404 | 0.73 | SMN1; SMN2 (0.44) | FPR2RAB9AFFAR2ADAM17HTT | |
| SCHEMBL7371393 | 0.73 | RAB9A (0.43) | FPR2RAB9AFFAR2ADAM17HTT | |
| SCHEMBL7372936 | 0.72 | ADAM17 (0.43) | FPR2RAB9AFFAR2ADAM17HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865339-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997003783-A9 | METALLOPROTEINASE INHIBITORS | — | 1997-04-03 | — | — | WO | disclosed |
| WO-1997003783-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |