Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 7/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | CDK14 | O94921 | 3/20 | 0.35 |
| ▸ | CCNY | Q8ND76 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597841 | 0.91 | PTGES (0.37) | PTGESCDK14CCNYTYK2P2RX7 | |
| SCHEMBL8599534 | 0.80 | LMNA (0.41) | PTGESLMNATYK2 | |
| SCHEMBL8670347 | 0.79 | MAPT (0.48) | PTGESMAPTAURKAAURKB | |
| SCHEMBL8601415 | 0.78 | LMNA (0.46) | PTGESLMNATYK2 | |
| SCHEMBL8598883 | 0.77 | TYK2 (0.44) | PTGESLMNATYK2P2RX7 | |
| SCHEMBL8599739 | 0.76 | KMT2A (0.41) | PTGESLMNA | |
| SCHEMBL8598365 | 0.75 | TYK2 (0.44) | PTGESTYK2 | |
| SCHEMBL8596975 | 0.75 | TYK2 (0.38) | PTGESTYK2MAPTP2RX7 | |
| SCHEMBL8597242 | 0.74 | LMNA (0.37) | PTGESLMNATYK2 | |
| Hydrochloric Acid SCHEMBL8600673 | 0.74 | TYK2 (0.38) | PTGESTYK2MAPTP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |