SCHEMBL8670372

SCHEMBL8670372

Cc1ccc([N+](=O)[O-])c2c1C(=O)c1ccccc1-2

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.60
PTPRC P08575 1/20 0.60
MAPT P10636 4/20 0.59
POLB P06746 1/20 0.59
APEX1 P27695 1/20 0.59
CASP6 P55212 1/20 0.59
ALDH1A1 P00352 7/20 0.58
CYP3A4 P08684 5/20 0.58
TSHR P16473 4/20 0.58
MAPK1 P28482 2/20 0.49
HSD17B10 Q99714 2/20 0.49
TP53 P04637 2/20 0.49
HIF1A Q16665 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
STAT6 P42226 1/20 0.49
PHLPP2 Q6ZVD8 1/20 0.49
CSNK2A2 P19784 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14922766 0.84 S100A4 (0.62) S100A4PTPRCMAPTPOLBAPEX1
SCHEMBL5109566 0.84 MAPT (0.79) S100A4PTPRCMAPTPOLBAPEX1
SCHEMBL12110300 0.82 TSHR (0.60) S100A4PTPRCMAPTPOLBAPEX1
SCHEMBL9267831 0.80 ALDH1A1 (0.62) S100A4PTPRCMAPTPOLBALDH1A1
SCHEMBL30886455 0.80 ALDH1A1 (0.67) S100A4PTPRCMAPTPOLBALDH1A1
SCHEMBL55743 0.80 ALDH1A1 (0.67) S100A4PTPRCMAPTPOLBALDH1A1
SCHEMBL11502323 0.79 S100A4 (0.54) S100A4PTPRCMAPTPOLBAPEX1
Ethyl Chloride SCHEMBL28265071 0.78 S100A4 (0.54) S100A4PTPRCMAPTPOLBAPEX1
SCHEMBL8777833 0.78 POLB (0.66) S100A4PTPRCMAPTPOLBAPEX1
SCHEMBL14680508 0.78 S100A4 (0.68) S100A4PTPRCMAPTPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0886182-A1 Positive photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-23 EP disclosed
EP-0385185-B1 Electrophotographic photoreceptor MITSUBISHI PAPER MILLS LTD (JP) 1994-05-18 EP disclosed
US-5141831-A Indole derivatives MITSUBISHI PAPER MILLS LIMITED (JP) 1992-08-25 US disclosed
US-5089366-A High sensitivity, durability MITSUBISHI PAPER MILLS LIMITED (JP) 1992-02-18 US disclosed
US-5013623-A Sensitivity and durability, lithographic printing plates MITSUBISHI PAPER MILLS LIMITED (JP) 1991-05-07 US disclosed
US-5009976-A Hydrazone compound as carrier transport material MITSUBISHI PAPER MILLS LIMITED (JP) 1991-04-23 US disclosed
EP-0385185-A2 Electrophotographic photoreceptor MITSUBISHI PAPER MILLS, LTD. (JP) 1990-09-05 EP disclosed
US-4567126-A HIGH SENSITIVITY AND DURABILITY MITSUBISHI PAPER MILLS, LTD. (JP) 1986-01-28 US disclosed