Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2865755 | 0.84 | GPR3 (0.30) | — | |
| Hydrochloric Acid SCHEMBL8673075 | 0.82 | NR3C1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL8673001 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL2866641 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL7991740 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL8669597 | 0.73 | HTR2A (0.32) | — | |
| Hydrochloric Acid SCHEMBL2859584 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL2869105 | 0.70 | CYP1A2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7934161 | 0.69 | NSD2 (0.35) | NSD2ALDH1A1EGFRLMNAMAPT | |
| Hydrochloric Acid SCHEMBL9412836 | 0.66 | NSD2 (0.35) | NSD2ALDH1A1EGFRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710222-A | CATALYTIC POLYMERIZATION OF PROPYLENE WITH METALLOCENE COMPOUND WITH GROUP IVB METAL AND EXTRATION | FINA TECHNOLOGY, INC. (US) | 1998-01-20 | — | — | US | claimed |