Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6916596 | 0.85 | GPR3 (0.31) | NSD2ALDH1A1EGFRLMNAMAPT | |
| Hydrochloric Acid SCHEMBL524858 | 0.82 | GPR3 (0.33) | — | |
| Methane SCHEMBL5348855 | 0.81 | GPR3 (0.32) | — | |
| Hydrochloric Acid SCHEMBL7193570 | 0.80 | NR3C1 (0.39) | ALDH1A1EGFRMAPTTDP1PDK2 | |
| Cyclopentane SCHEMBL6557619 | 0.80 | BCHE (0.33) | — | |
| Fluoride Ion SCHEMBL1130995 | 0.79 | GPR3 (0.33) | — | |
| Methane SCHEMBL7939292 | 0.79 | MTNR1A (0.32) | ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7180983 | 0.78 | GPR3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7621841 | 0.78 | GPR3 (0.31) | — | |
| Propene SCHEMBL27558553 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773239-B1 | Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems | FINA TECHNOLOGY (US) | 2001-12-05 | — | — | EP | claimed |