Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 16/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598379 | 0.71 | ALDH1A1 (0.41) | TRPV1KDM4EHPGD | |
| SCHEMBL8596744 | 0.70 | TRPV1 (0.41) | P2RX7TRPV1DRD2DRD4DRD3 | |
| SCHEMBL8670592 | 0.68 | KMT2A (0.38) | KDM4E | |
| SCHEMBL8670588 | 0.63 | RORC (0.35) | — | |
| SCHEMBL8670583 | 0.62 | TSHR (0.35) | KDM4E | |
| SCHEMBL29935873 | 0.61 | MEN1 (0.58) | TRPV1DRD2DRD4DRD3KDM4E | |
| SCHEMBL28610898 | 0.61 | MEN1 (0.58) | TRPV1DRD2DRD4DRD3KDM4E | |
| SCHEMBL8599475 | 0.61 | TRPV1 (0.65) | TRPV1KDM4EHPGD | |
| SCHEMBL4573462 | 0.59 | TDP1 (0.45) | DRD2DRD4DRD3KDM4E | |
| SCHEMBL27921631 | 0.58 | PIK3C2B (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |