Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.42 |
| ▸ | DRD3 | P35462 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559247 | 0.90 | DRD2 (0.46) | DRD2DRD3 | |
| SCHEMBL8557936 | 0.83 | CHRNA7 (0.43) | KDM4EGAALMNAMAPT | |
| SCHEMBL8051844 | 0.80 | MEN1 (0.53) | DRD2DRD3KDM4EGAAHTR2A | |
| SCHEMBL9286378 | 0.78 | LMNA (0.59) | DRD2DRD3LMNAHTR1AHTR2A | |
| SCHEMBL8555321 | 0.77 | HRH4 (0.42) | MAPT | |
| SCHEMBL26493117 | 0.72 | HTR1A (0.58) | DRD2DRD3KDM4ELMNAHTR1A | |
| SCHEMBL20835002 | 0.72 | HTR1A (0.58) | DRD2DRD3KDM4ELMNAHTR1A | |
| SCHEMBL9535253 | 0.72 | HTR1A (0.58) | DRD2DRD3KDM4ELMNAHTR1A | |
| SCHEMBL27954074 | 0.72 | SIGMAR1 (0.64) | — | |
| SCHEMBL8559854 | 0.70 | HRH1 (0.37) | TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883606-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | claimed |
| WO-1997031893-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | claimed |