Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669264 | 0.81 | NPC1 (0.44) | MTNR1AMTNR1B | |
| SCHEMBL4857120 | 0.75 | CA1 (0.45) | MTNR1AMTNR1B | |
| SCHEMBL6953263 | 0.75 | CA1 (0.45) | MTNR1AMTNR1B | |
| SCHEMBL5982154 | 0.73 | CA2 (0.41) | MTNR1AMTNR1B | |
| SCHEMBL10043010 | 0.73 | DRD2 (0.57) | MTNR1AMTNR1BDRD2 | |
| SCHEMBL3318329 | 0.73 | DRD2 (0.57) | MTNR1AMTNR1BDRD2 | |
| SCHEMBL6954327 | 0.71 | DRD2 (0.51) | DRD2 | |
| SCHEMBL27341732 | 0.71 | MTNR1A (0.51) | MTNR1AMTNR1B | |
| SCHEMBL6954331 | 0.71 | DRD2 (0.51) | DRD2 | |
| SCHEMBL6958607 | 0.71 | DRD2 (0.51) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017832-A1 | NOVEL GLUTAMATE RECEPTOR ANTAGONISTS: FUSED CYCLOALKYLQUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1996-06-13 | — | — | WO | claimed |
| US-5721234-A | TREATING CONVULSIONS, ANXIETY, CEREBRAL HYPOXIA/ISCHEMIA, PARKINSON*S DISEASE | WARNER-LAMBERT COMPANY (US) | 1998-02-24 | — | — | US | disclosed |
| WO-1996017832-A1 | NOVEL GLUTAMATE RECEPTOR ANTAGONISTS: FUSED CYCLOALKYLQUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1996-06-13 | — | — | WO | disclosed |