Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 6/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679527 | 0.81 | ALDH1A1 (0.50) | GPR35TSHRCYP3A4KDM4ETDP1 | |
| SCHEMBL7597811 | 0.78 | TSHR (0.62) | GPR35TSHRCYP3A4TDP1HSD17B10 | |
| SCHEMBL8675771 | 0.77 | TDP1 (0.60) | GPR35TSHRTDP1HSD17B10ALDH1A1 | |
| SCHEMBL260768 | 0.77 | GPR35 (0.67) | GPR35TSHRCYP3A4KDM4ETDP1 | |
| SCHEMBL11802737 | 0.75 | GPR35 (0.64) | GPR35TSHRCYP3A4KDM4ETDP1 | |
| SCHEMBL12863895 | 0.74 | GPR35 (0.57) | GPR35TSHRCYP3A4KDM4ETDP1 | |
| SCHEMBL699870 | 0.74 | TSHR (0.60) | GPR35TSHRTDP1HSD17B10ALDH1A1 | |
| SCHEMBL322531 | 0.73 | GPR35 (1.00) | GPR35TSHRCYP3A4KDM4ETDP1 | |
| SCHEMBL19420578 | 0.73 | GPR35 (0.61) | GPR35TSHRCYP3A4KDM4ETDP1 | |
| Benzene SCHEMBL27490159 | 0.73 | GPR35 (0.61) | GPR35TSHRCYP3A4KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710311-A | 2-sulphured metaphenylenediamines for dyeing hair | L'OREAL (FR) | 1998-01-20 | — | — | US | disclosed |
| EP-0586660-B1 | 2-SULPHURED METAPHENYLENEDIAMINES FOR DYEING HAIR | OREAL (FR) | 1997-01-29 | — | — | EP | disclosed |
| US-5505741-A | DYEING HAIR BY OXIDATION, RINSING, WASHING WITH SHAMPOO, RINSING AND DRYING | L'OREAL (FR) | 1996-04-09 | — | — | US | disclosed |