Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671772 | 0.81 | GPR35 (0.57) | ALDH1A1CYP3A4TSHRRECQLTDP1 | |
| SCHEMBL29593492 | 0.79 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TSHRRECQLTDP1 | |
| SCHEMBL11144762 | 0.79 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TSHRRECQLTDP1 | |
| SCHEMBL314000 | 0.76 | TSHR (0.61) | ALDH1A1CYP3A4TSHRRECQLTDP1 | |
| SCHEMBL8675771 | 0.76 | TDP1 (0.60) | ALDH1A1TSHRTDP1L3MBTL1HSD17B10 | |
| SCHEMBL5080205 | 0.75 | ALDH1A1 (0.58) | ALDH1A1CYP3A4TSHRRECQLTDP1 | |
| SCHEMBL10400389 | 0.75 | ALDH1A1 (0.58) | ALDH1A1CYP3A4TSHRRECQLTDP1 | |
| SCHEMBL11802635 | 0.73 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRRECQLTDP1 | |
| SCHEMBL10943186 | 0.73 | TDP1 (0.56) | ALDH1A1CYP3A4TSHRRECQLTDP1 | |
| SCHEMBL19071954 | 0.71 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TSHRRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710311-A | 2-sulphured metaphenylenediamines for dyeing hair | L'OREAL (FR) | 1998-01-20 | — | — | US | disclosed |
| EP-0586660-B1 | 2-SULPHURED METAPHENYLENEDIAMINES FOR DYEING HAIR | OREAL (FR) | 1997-01-29 | — | — | EP | disclosed |
| US-5505741-A | DYEING HAIR BY OXIDATION, RINSING, WASHING WITH SHAMPOO, RINSING AND DRYING | L'OREAL (FR) | 1996-04-09 | — | — | US | disclosed |
| EP-0586660-A1 | 2-SULPHURED METAPHENYLENEDIAMINES FOR DYEING HAIR. | OREAL (FR) | 1994-03-16 | — | — | EP | disclosed |
| WO-1993018739-A1 | 2-SULPHURED METAPHENYLENEDIAMINES FOR DYEING HAIR | L'OREAL (FR) | 1993-09-30 | — | — | WO | disclosed |