SCHEMBL8672147

SCHEMBL8672147

CCC(N)(C(=O)O)C(=O)OCc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.48
IDO1 P14902 2/20 0.48
MAOB P27338 1/20 0.47
ALDH1A1 P00352 3/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.45
HTR2A P28223 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8940536 0.84 MAOB (0.49) RAB9AIDO1MAOBALDH1A1POLB
SCHEMBL8940532 0.82 MAOB (0.52) RAB9AIDO1MAOBALDH1A1POLB
SCHEMBL4550673 0.82 ALDH1A1 (0.51) RAB9AALDH1A1MAPTL3MBTL1
SCHEMBL7476437 0.82 ALDH1A1 (0.51) RAB9AALDH1A1MAPTL3MBTL1
SCHEMBL8643594 0.82 ALDH1A1 (0.51) RAB9AALDH1A1MAPTL3MBTL1
SCHEMBL2234344 0.81 HTR2A (0.52) RAB9AIDO1MAOBALDH1A1MAPT
Hydrochloric Acid SCHEMBL11265034 0.80 ALDH1A1 (0.50) RAB9AALDH1A1MAPTL3MBTL1
SCHEMBL8572371 0.80 IDO1 (0.51) RAB9AIDO1MAOBALDH1A1POLB
SCHEMBL9976430 0.79 ALDH1A1 (0.55) RAB9AIDO1MAOBALDH1A1POLB
SCHEMBL2548548 0.78 MAOB (0.44) RAB9AIDO1MAOBALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750735-A CHEMICAL INTERMEDIATES FOR ANTIBIOTICS AMERICAN CYANAMID COMPANY (US) 1998-05-12 US disclosed