SCHEMBL8673176

SCHEMBL8673176

C=CCc1[c]c(C(C)(C)C)cc(C(C)(C)C)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1720320 0.79 HTR1D (0.36)
SCHEMBL1291247 0.79 GABRA1 (0.34)
SCHEMBL27369343 0.77 GABRA1 (0.33)
SCHEMBL27341965 0.76 HTR1D (0.38)
SCHEMBL8973438 0.74
SCHEMBL150439 0.73 GABRA1 (0.43)
SCHEMBL10412824 0.73 TNKS (0.37)
SCHEMBL11305609 0.69 ALDH1A1 (0.38)
SCHEMBL15549564 0.69 GABRA1 (0.41)
SCHEMBL3121979 0.68 GABRA1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0702054-B1 Polyolefin fiber and film GEN ELECTRIC (US) 1998-12-23 EP disclosed
EP-0701890-B1 Melt extrusion process GEN ELECTRIC (US) 1998-12-16 EP disclosed
US-5605947-A STABILIZERS FOR THERMOPLASTIC RESINS HAVING IMPROVED HYDROLYTIC STABILITY AND RESISTANCE TO ULTRAVIOLET LIGHT YELLOWING GENERAL ELECTRIC COMPANY (US) 1997-02-25 US disclosed
US-5543102-A MELTING, FILTERING AND MOLDING NEO-ALKYL PHENYL PHOSPHITE STABILZED POLYOLEFIN TO FORM FIBER OR FILM GENERAL ELECTRIC COMPANY (US) 1996-08-06 US disclosed
EP-0701890-A1 Melt extrusion process GENERAL ELECTRIC COMPANY (US) 1996-03-20 EP disclosed
EP-0702018-A1 Amorphous neo-diol phosphite compositions GENERAL ELECTRIC COMPANY (US) 1996-03-20 EP disclosed
EP-0702054-A1 Polyolefin fiber and film GENERAL ELECTRIC COMPANY (US) 1996-03-20 EP disclosed
US-5500467-A PHOSPHITES, DISCOLORATION INHIBITION GENERAL ELECTRIC COMPANY (US) 1996-03-19 US disclosed