Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9651473 | 0.90 | TAS2R14 (0.48) | HSD11B1KMT2AMEN1HDAC1HDAC6 | |
| SCHEMBL14855018 | 0.88 | KMT2A (0.49) | KMT2AMEN1TDP1TSHRKDM4E | |
| SCHEMBL6551303 | 0.85 | HSD11B1 (0.51) | HSD11B1KMT2AMEN1HDAC1HDAC6 | |
| SCHEMBL14855305 | 0.84 | GAA (0.66) | KMT2AMEN1TDP1TSHRKDM4E | |
| SCHEMBL7405546 | 0.84 | NPC1 (0.48) | KMT2AMEN1TDP1TSHRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11685888 | 0.82 | NPC1 (0.47) | KMT2AMEN1TDP1TSHRL3MBTL1 | |
| SCHEMBL14493279 | 0.81 | ALDH1A1 (0.42) | HSD11B1KMT2AMEN1TDP1TSHR | |
| SCHEMBL10296224 | 0.81 | GSK3B (0.45) | HSD11B1KMT2AMEN1TDP1TSHR | |
| SCHEMBL12650288 | 0.81 | ALDH1A1 (0.53) | KMT2AMEN1HDAC1HDAC6TDP1 | |
| SCHEMBL1003508 | 0.79 | HDAC1 (0.71) | HSD11B1KMT2AMEN1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128488-A | Phosphorus-metal complex catalyst | SOCIETE CHIMIQUE DES CHARBONNAGES S.A. (FR) | 1992-07-07 | — | — | US | claimed |
| EP-0253700-B1 | PROCESS FOR THE ASYMMETRIC HYDROGENATION OF CARBONYL COMPOUNDS, AND THE COMPOUNDS OBTAINED THEREBY | ELF ATOCHEM S.A. (FR) | 1990-08-29 | — | — | EP | claimed |
| EP-0253700-A1 | Process for the asymmetric hydrogenation of carbonyl compounds, and the compounds obtained thereby | ELF ATOCHEM S.A. (FR) | 1988-01-20 | — | — | EP | claimed |
| WO-1987007889-A1 | ASYMETRIC HYDROGENATION PROCESS FOR CARBONYL COMPOUNDS, AND COMPOUNDS OBTAINED | SOCIETE CHIMIQUE DES CHARBONNAGES S.A. (FR) | 1987-12-30 | — | — | WO | claimed |
| US-5834588-A | (Cyanomethylene) phosphoranes as carbonyl 1,1-dipole synthons for use in constructing combinatorial libraries | YALE UNIVERSITY (US) | 1998-11-10 | — | — | US | disclosed |
| EP-0443923-B1 | New aminophosphine-phosphinites, their process and their use for enantio-selective reactions | SANOFI SA (FR) | 1997-08-27 | — | — | EP | disclosed |
| US-5128488-A | Phosphorus-metal complex catalyst | SOCIETE CHIMIQUE DES CHARBONNAGES S.A. (FR) | 1992-07-07 | — | — | US | disclosed |
| EP-0443923-A1 | New aminophosphine-phosphinites, their process and their use for enantio-selective reactions | SANOFI (FR) | 1991-08-28 | — | — | EP | disclosed |
| EP-0253700-B1 | PROCESS FOR THE ASYMMETRIC HYDROGENATION OF CARBONYL COMPOUNDS, AND THE COMPOUNDS OBTAINED THEREBY | ELF ATOCHEM S.A. (FR) | 1990-08-29 | — | — | EP | disclosed |
| EP-0253700-A1 | Process for the asymmetric hydrogenation of carbonyl compounds, and the compounds obtained thereby | ELF ATOCHEM S.A. (FR) | 1988-01-20 | — | — | EP | disclosed |
| WO-1987007889-A1 | ASYMETRIC HYDROGENATION PROCESS FOR CARBONYL COMPOUNDS, AND COMPOUNDS OBTAINED | SOCIETE CHIMIQUE DES CHARBONNAGES S.A. (FR) | 1987-12-30 | — | — | WO | disclosed |