SCHEMBL6551303

SCHEMBL6551303

C=CN(Cc1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.51
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
HDAC3 O15379 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
TSHR P16473 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.47
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
AKT1 P31749 1/20 0.45
GAA P10253 1/20 0.45
CTSS P25774 2/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28394274 0.88 AGER (0.55) KMT2AMEN1HDAC3HDAC1HDAC7
SCHEMBL3333332 0.86 TDP1 (0.50) HSD11B1KMT2AMEN1TDP1TSHR
SCHEMBL8673185 0.85 HSD11B1 (0.51) HSD11B1KMT2AMEN1HDAC3HDAC1
SCHEMBL28398835 0.84 NR1H4 (0.57) KMT2AMEN1HDAC3HDAC1HDAC7
SCHEMBL8415306 0.82 AKT1 (0.47) KMT2AMEN1HDAC3HDAC1TDP1
SCHEMBL13198360 0.81 GSTO1 (0.47) KMT2AMEN1TDP1TSHRKDM4E
SCHEMBL3120142 0.81 TSPO (0.47) KMT2AMEN1TDP1TSHRCRHBP
SCHEMBL6551871 0.81 ALDH1A1 (0.53) HDAC1HDAC6TSHRL3MBTL1LMNA
SCHEMBL1003508 0.79 HDAC1 (0.71) HSD11B1KMT2AMEN1HDAC3HDAC1
SCHEMBL6551332 0.79 AKT1 (0.44) KMT2AMEN1HDAC3HDAC1HDAC10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111187176-B Method for preparing N-vinyl amide compound under catalysis of copper salt 浙江工业大学 2022-11-25 CN disclosed
CN-111187176-A Method for preparing N-vinyl amide compound under catalysis of copper salt 浙江工业大学 2020-05-22 CN disclosed
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 EP disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed