Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9476401 | 0.88 | HTT (0.40) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL24106248 | 0.87 | HTT (0.42) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL15430979 | 0.80 | HTT (0.41) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL15443899 | 0.80 | HTT (0.45) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL9863293 | 0.79 | PREP (0.36) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL26851800 | 0.78 | CYP1A2 (0.38) | HTTKDM4EHSD17B10GAAMAPT | |
| SCHEMBL3156904 | 0.77 | KDM4E (0.52) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL7112659 | 0.77 | ACHE (0.42) | HTTKDM4EHSD17B10GAAMAPT | |
| SCHEMBL22991742 | 0.76 | HTT (0.39) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL1379951 | 0.76 | LMNA (0.46) | KDM4EHSD17B10TP53MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807947-A | BINDER FOR PHOTORESISTS | CLARIANT FINANCE (BVI) LIMITED (VG) | 1998-09-15 | — | — | US | disclosed |
| EP-0365340-B1 | Copolymers of 4-hydroxystyrene and alkyl substituted-4-hydroxystyrene | HOECHST CELANESE CORP (US) | 1995-05-03 | — | — | EP | disclosed |
| EP-0307752-B1 | Poly(3-mono- and 3,5-disubstituted-4-acetoxystyrenes and 4-hydroxy-styrenes)and their use | HOECHST AG (DE) | 1995-02-22 | — | — | EP | disclosed |
| US-5342727-A | Copolymers of 4-hydroxystyrene and alkyl substituted-4-hydroxystyrene in admixture with a photosensitizer to form a photosensitive composition | HOECHST CELANESE CORP. (US) | 1994-08-30 | — | — | US | disclosed |
| US-5072025-A | Process for the production of 3,5-disubstituted-4-acetoxystyrene | HOECHST CELANESE CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| US-5072025-A | Process for the production of 3,5-disubstituted-4-acetoxystyrene | HOECHST CELANESE CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| US-4965400-A | Preparation of 3,5-disubstituted-4-acetoxystyrene | CLARIANT AG (CH) | 1990-10-23 | — | — | US | disclosed |
| US-4965400-A | Preparation of 3,5-disubstituted-4-acetoxystyrene | CLARIANT AG (CH) | 1990-10-23 | — | — | US | disclosed |
| US-4927956-A | 3,5-disubstituted-4-acetoxystyrene and process for its production | HOECHST CELANESE CORPORATION (US) | 1990-05-22 | — | — | US | disclosed |
| US-4927956-A | 3,5-disubstituted-4-acetoxystyrene and process for its production | HOECHST CELANESE CORPORATION (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0365340-A2 | Copolymers of 4-hydroxystyrene and alkyl substituted-4-hydroxystyrene | HOECHST CELANESE CORPORATION (US) | 1990-04-25 | — | — | EP | disclosed |
| EP-0356070-A1 | Synthesis of 4-acetoxystyrene oxide and related compounds | HOECHST CELANESE CORPORATION (US) | 1990-02-28 | — | — | EP | disclosed |
| EP-0307751-A2 | 3-mono- and 3,5-disubstituted-4-acetoxy and -4-hydroxystyrenes and process for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-22 | — | — | EP | disclosed |
| EP-0307752-A2 | Poly(3-mono- and 3,5-disubstituted-4-acetoxystyrenes and 4-hydroxy-styrenes)and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-22 | — | — | EP | disclosed |