Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9476401 | 0.90 | HTT (0.40) | PREPMEN1KMT2ACA2BACE1 | |
| SCHEMBL8673246 | 0.79 | HTT (0.45) | PREPBACE1HTTHSD17B10KDM4E | |
| SCHEMBL6936490 | 0.78 | PREP (0.46) | PREPMEN1KMT2ACA2BACE1 | |
| SCHEMBL4647729 | 0.78 | HSD17B10 (0.50) | PREPMEN1KMT2ACA2BACE1 | |
| SCHEMBL7827341 | 0.76 | PREP (0.48) | PREPMEN1KMT2ACA2BACE1 | |
| SCHEMBL13864993 | 0.76 | BACE1 (0.50) | PREPMEN1KMT2ACA2BACE1 | |
| SCHEMBL14430071 | 0.76 | KDM4E (0.44) | PREPMEN1KMT2ACA2BACE1 | |
| SCHEMBL19726450 | 0.75 | TSHR (0.43) | HTTHSD17B10TP53MAPT | |
| SCHEMBL9863397 | 0.75 | TPMT (0.42) | PREPMEN1KMT2ACA2BACE1 | |
| SCHEMBL1379951 | 0.75 | LMNA (0.46) | MEN1KMT2ABACE1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072025-A | Process for the production of 3,5-disubstituted-4-acetoxystyrene | HOECHST CELANESE CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| US-4965400-A | Preparation of 3,5-disubstituted-4-acetoxystyrene | CLARIANT AG (CH) | 1990-10-23 | — | — | US | disclosed |
| US-4933495-A | Process for the production of 3-mono or 3,5 dihalogenated 4-acetoxystyrene, its polymerization, and hydrolysis | HOECHST CELANESE CORPORATION (US) | 1990-06-12 | — | — | US | disclosed |
| US-4927956-A | 3,5-disubstituted-4-acetoxystyrene and process for its production | HOECHST CELANESE CORPORATION (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0356070-A1 | Synthesis of 4-acetoxystyrene oxide and related compounds | HOECHST CELANESE CORPORATION (US) | 1990-02-28 | — | — | EP | disclosed |
| EP-0353339-A2 | A process for the production of poly(3-mono or 3,5-disubstituted-4-Acetoxystryrenes), their copolymers and hydrolysis thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-07 | — | — | EP | disclosed |
| US-4868257-A | Process for the production of 3-mono or 3,5 disubstituted-4-acetoxystyrene, its polymerization | HOECHST CELANESE CORPORATION (US) | 1989-09-19 | — | — | US | disclosed |
| US-4868256-A | Process for the production of 3-mono or 3,5-disubstituted-4-acetoxystyrene its polymerization, and hydrolysis | HOECHST CELANESE (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0307751-A2 | 3-mono- and 3,5-disubstituted-4-acetoxy and -4-hydroxystyrenes and process for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-22 | — | — | EP | disclosed |