Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31587740 | 0.87 | LMNA (0.56) | MEN1KMT2AKDM4EPARP1LMNA | |
| SCHEMBL7848611 | 0.86 | MEN1 (0.46) | MEN1KMT2AKDM4EPARP1LMNA | |
| SCHEMBL3972659 | 0.84 | AGTR1 (0.45) | KDM4ELMNAHPGDALDH1A1GAA | |
| SCHEMBL951984 | 0.82 | LMNA (0.55) | MEN1KMT2AKDM4ELMNAHPGD | |
| SCHEMBL8410524 | 0.81 | MEN1 (0.43) | MEN1KMT2AKDM4EPARP1LMNA | |
| SCHEMBL8671748 | 0.80 | MEN1 (0.51) | MEN1KMT2AKDM4EPARP1LMNA | |
| SCHEMBL9179529 | 0.80 | MEN1 (0.53) | MEN1KMT2AKDM4EPARP1LMNA | |
| SCHEMBL8412379 | 0.79 | AGTR1 (0.48) | MEN1KMT2AKDM4ELMNACYP1A2 | |
| SCHEMBL8673292 | 0.78 | KDM4E (0.55) | MEN1KMT2AKDM4EPARP1LMNA | |
| SCHEMBL8671753 | 0.78 | CYP1A2 (0.53) | MEN1KMT2AKDM4EPARP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817674-A | ANTIOTENSIN II RECEPTOR ANTAGONISTS | ROUSSEL UCLAF (FR) | 1998-10-06 | — | — | US | disclosed |