Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 7/20 | 0.47 |
| ▸ | CCKAR | P32238 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670033 | 0.89 | CCKBR (0.47) | CCKBRCCKARHDAC3HDAC1HDAC6 | |
| SCHEMBL8674133 | 0.87 | CCKBR (0.48) | CCKBRCCKARHDAC3HDAC1HDAC6 | |
| SCHEMBL8667954 | 0.87 | CCKBR (0.48) | CCKBRCCKARHDAC3HDAC1HDAC6 | |
| SCHEMBL8669315 | 0.84 | CCKBR (0.48) | CCKBRCCKARHDAC3HDAC1HDAC6 | |
| SCHEMBL8674533 | 0.83 | CCKBR (0.49) | CCKBRCCKARHDAC3HDAC1HDAC6 | |
| SCHEMBL8801102 | 0.81 | FNTA (0.52) | CCKBRCCKARHDAC3HDAC1HDAC6 | |
| SCHEMBL8676596 | 0.80 | CCKBR (0.48) | CCKBRCCKARHDAC3HDAC1HDAC6 | |
| SCHEMBL8669230 | 0.78 | HTR2B (0.45) | CCKBRCCKARSMN1; SMN2 | |
| SCHEMBL8801804 | 0.76 | FNTA (0.54) | CCKBRCCKARKDM4ESMN1; SMN2 | |
| SCHEMBL8676603 | 0.74 | CCKBR (0.48) | CCKBRCCKARHDAC3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |