Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 0.49 |
| ▸ | CCKAR | P32238 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667954 | 0.85 | CCKBR (0.48) | CCKBRCCKARHDAC3HDAC6HDAC1 | |
| SCHEMBL8674133 | 0.85 | CCKBR (0.48) | CCKBRCCKARHDAC3HDAC6HDAC1 | |
| SCHEMBL8674155 | 0.83 | CCKBR (0.47) | CCKBRCCKARHDAC3HDAC6HDAC1 | |
| SCHEMBL8670033 | 0.83 | CCKBR (0.47) | CCKBRCCKARHDAC3HDAC6HDAC1 | |
| SCHEMBL8669315 | 0.81 | CCKBR (0.48) | CCKBRCCKARHDAC3HDAC6HDAC1 | |
| SCHEMBL8801488 | 0.77 | FNTA (0.51) | CCKBRCCKARHDAC3HDAC6HDAC1 | |
| SCHEMBL8676596 | 0.77 | CCKBR (0.48) | CCKBRCCKARHDAC3HDAC6HDAC1 | |
| SCHEMBL8674526 | 0.77 | CCKBR (0.47) | CCKBRCCKARHDAC3HDAC6HDAC1 | |
| SCHEMBL8669230 | 0.75 | HTR2B (0.45) | CCKBRCCKARKCNH2TP53 | |
| SCHEMBL8800222 | 0.72 | FNTA (0.46) | CCKBRCCKARHDAC3HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |