Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 4/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674232 | 0.82 | MAPT (0.42) | ADRA2BADRA2CADRA2AADRA1AMAPT | |
| SCHEMBL8674172 | 0.71 | ADRA2A (0.50) | ADRA2BADRA2CADRA2AADRA1AMAPT | |
| SCHEMBL8672432 | 0.71 | MAPT (0.45) | ADRA2AADRA1AMAPTRGS12KDM4E | |
| SCHEMBL8671629 | 0.71 | SLC6A2 (0.32) | MAPTRGS12KDM4EMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL8674349 | 0.69 | ADRA2A (0.48) | ADRA2BADRA2CADRA2AADRA1AMAPT | |
| SCHEMBL8677169 | 0.62 | CYP1A2 (0.55) | ADRA2BADRA2CADRA2AADRA1ACYP1A2 | |
| SCHEMBL9562173 | 0.62 | TP53 (0.44) | ADRA2BADRA2CADRA2AMAPTMEN1 | |
| SCHEMBL10680232 | 0.60 | ADRA2A (0.53) | ADRA2BADRA2CADRA2AADRA1ACYP1A2 | |
| SCHEMBL8674126 | 0.59 | TIPARP (0.42) | ADRA2BADRA2CADRA2ACYP1A2KCNH2 | |
| SCHEMBL3737540 | 0.58 | ADRA1A (0.49) | ADRA2BADRA2CADRA2AADRA1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726197-A | ADRENORECEPTORS AND ADMINISTERING | SYNTEX (U.S.A.) INC. (US) | 1998-03-10 | — | — | US | disclosed |