Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 7/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.38 |
| ▸ | RBPJ | Q06330 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 3/20 | 0.37 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674221 | 0.91 | CCKBR (0.51) | CCKBRKCNH2OXTRCCKAR | |
| SCHEMBL8677097 | 0.84 | HTR2B (0.41) | CCKBRKCNH2BRD4BRD2BRD3 | |
| SCHEMBL8801524 | 0.81 | OXTR (0.48) | CCKBROXTR | |
| SCHEMBL8672564 | 0.79 | HTR2B (0.40) | CCKBRKCNH2BRD4BRD2BRD3 | |
| SCHEMBL8674482 | 0.79 | LMNA (0.44) | CCKBRKCNH2BRD4BRD2BRD3 | |
| SCHEMBL8670555 | 0.79 | LMNA (0.44) | CCKBRKCNH2BRD4BRD2BRD3 | |
| SCHEMBL8676259 | 0.77 | CCKBR (0.43) | CCKBRKCNH2BRD4BRD2BRD3 | |
| SCHEMBL8674323 | 0.77 | LMNA (0.42) | CCKBRKCNH2BRD4BRD2BRD3 | |
| SCHEMBL8667949 | 0.76 | NOTCH1 (0.42) | CCKBRKCNH2BRD4BRD2BRD3 | |
| SCHEMBL8674054 | 0.76 | PDE3A (0.41) | CCKBRKCNH2BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |