SCHEMBL867437

SCHEMBL867437

c1ccc2c3c(ccc2c1)-c1c(ccc2ccccc12)C3

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.43
ANPEP P15144 1/20 0.42
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 3/20 0.41
CYP2A6 P11509 1/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP1A2 P05177 3/20 0.38
HPGD P15428 3/20 0.38
CYP2C19 P33261 3/20 0.38
KDM4E B2RXH2 2/20 0.38
HTT P42858 1/20 0.38
CDK5 Q00535 1/20 0.38
CDK5R1 Q15078 1/20 0.38
NCOA1 Q15788 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NCOA3 Q9Y6Q9 1/20 0.38
HPRT1 P00492 1/20 0.38
MAPT P10636 1/20 0.37
WDR5 P61964 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30585509 1.00 DNMT1 (0.43) DNMT1ANPEPALDH1A1HSD17B10CYP2A6
SCHEMBL4852568 0.87 ANPEP (0.40) DNMT1ANPEPALDH1A1HSD17B10CYP2A6
SCHEMBL22076938 0.81 DNMT1 (0.41) DNMT1ANPEPALDH1A1HSD17B10CYP2A6
SCHEMBL30585507 0.79 ANPEP (0.41) ANPEPALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL1155357 0.79 ANPEP (0.41) ANPEPALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL2535555 0.79 ANPEP (0.55) ANPEPALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL868515 0.79 ALDH1A1 (0.52) DNMT1ANPEPALDH1A1HSD17B10CYP2A6
SCHEMBL29811500 0.79 ANPEP (0.55) ANPEPALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL31274510 0.79 ANPEP (0.55) ANPEPALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL29716676 0.79 TSHR (0.52) DNMT1ANPEPALDH1A1HSD17B10CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116669571-A Flavoring composition 弗门尼舍有限公司 2023-08-29 CN claimed
US-20120074336-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE (US) 2012-03-29 US claimed
US-7964722-B2 Light-driven rotary molecular motors BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) 2011-06-21 US claimed
US-20110077394-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS NATIONAL SCIENCE FOUNDATION 2011-03-31 US claimed
US-11555028-B2 Organic compound and photoelectric conversion element CANON KABUSHIKI KAISHA (JP) 2023-01-17 US disclosed
US-20190119258-A1 ORGANIC COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT CANON KABUSHIKI KAISHA (JP) 2019-04-25 US disclosed
US-20120074336-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE (US) 2012-03-29 US disclosed
US-7964722-B2 Light-driven rotary molecular motors BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) 2011-06-21 US disclosed
US-20110077394-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS NATIONAL SCIENCE FOUNDATION 2011-03-31 US disclosed
US-7838130-B2 Aminodibenzofluorene derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2010-11-23 US disclosed
US-20090267491-A1 AMINODIBENZOFLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-10-29 US disclosed
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-20020103191-A1 Antitumor dibenzofluorene derivatives BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2002-08-01 US disclosed
EP-1218370-A2 QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS Aventis Pharma S.A. (FR) 2002-07-03 EP disclosed
US-6362200-B1 ANTICANCER AGENTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2002-03-26 US disclosed
EP-1135379-A1 ANTITUMOR DIBENZOFLUORENE DERIVATIVES Board of Regents, The University of Texas System (US) 2001-09-26 EP disclosed
WO-2001025227-A2 QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS AVENTIS PHARMA S.A. (FR) 2001-04-12 WO disclosed
US-6184224-B1 DRUG RESISTANCE AND SIDE EFFECT REDUCTION BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2001-02-06 US disclosed
WO-2000032583-A9 ANTITUMOR DIBENZOFLUORENE DERIVATIVES UNIV TEXAS (US) 2000-11-30 WO disclosed
WO-2000032583-A1 ANTITUMOR DIBENZOFLUORENE DERIVATIVES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2000-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090267491-A1 AMINODIBENZOFLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME L1CAM, DDC, LEF1 DNMT1 593/4885ANPEP 566/4885ALDH1A1 35/4885
US-20020103191-A1 Antitumor dibenzofluorene derivatives MCL1, HNRNPF, KRAS DNMT1 3026/4885ANPEP 2146/4885ALDH1A1 782/4885
US-20110077394-A1 LIGHT-DRIVEN ROTARY MOLECULAR MOTORS CCNA2, CCNO, SCO2 DNMT1 1555/4885ANPEP 4788/4885ALDH1A1 4255/4885
US-20190119258-A1 ORGANIC COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT SCN2B, MRPS22, CTNNA1 DNMT1 467/4885ANPEP 3652/4885ALDH1A1 908/4885
US-11555028-B2 Organic compound and photoelectric conversion element SCN2B, MRPS22, CTNNA1 DNMT1 467/4885ANPEP 3652/4885ALDH1A1 908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.