Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341109 | 0.88 | SGMS2 (0.62) | SGMS2NPC1HTTGAAFAAH | |
| SCHEMBL9805921 | 0.79 | SGMS2 (0.57) | SGMS2NPC1HTTGAAMEN1 | |
| SCHEMBL7774921 | 0.79 | RXRA (0.58) | SGMS2NPC1HTTPARP1PTGER1 | |
| SCHEMBL28181099 | 0.79 | CHRM4 (0.53) | SGMS2NPC1HTTGAAFAAH | |
| SCHEMBL6476026 | 0.79 | SGMS2 (0.52) | SGMS2NPC1HTTGAAFAAH | |
| SCHEMBL8677136 | 0.79 | SGMS2 (0.60) | SGMS2NPC1HTTGAAMEN1 | |
| SCHEMBL27723974 | 0.78 | SGMS2 (0.59) | SGMS2NPC1HTTGAAMEN1 | |
| SCHEMBL8674677 | 0.78 | PTGER1 (0.54) | SGMS2NPC1HTTGAAMEN1 | |
| SCHEMBL2331143 | 0.78 | MAPT (0.65) | SGMS2NPC1HTTGAAMEN1 | |
| SCHEMBL29433417 | 0.77 | SGMS2 (0.66) | SGMS2NPC1HTTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |