Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 6/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1927224 | 0.90 | SGMS2 (0.74) | SGMS2L3MBTL1LMNAMAPTALDH1A1 | |
| SCHEMBL8980612 | 0.82 | SGMS2 (0.70) | SGMS2L3MBTL1LMNAMAPTALDH1A1 | |
| SCHEMBL8677139 | 0.79 | PTGER1 (0.57) | SGMS2L3MBTL1LMNAMAPTALDH1A1 | |
| SCHEMBL8674882 | 0.79 | SGMS2 (0.54) | SGMS2L3MBTL1LMNAMAPTALDH1A1 | |
| SCHEMBL18644999 | 0.78 | SGMS2 (0.72) | SGMS2L3MBTL1LMNAMAPTALDH1A1 | |
| SCHEMBL3018273 | 0.77 | SGMS2 (0.76) | SGMS2L3MBTL1LMNAMAPTALDH1A1 | |
| SCHEMBL8980728 | 0.76 | SGMS2 (0.70) | SGMS2L3MBTL1LMNAMAPTALDH1A1 | |
| SCHEMBL8894839 | 0.74 | ALDH1A1 (0.62) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11291711 | 0.74 | SGMS2 (0.70) | SGMS2L3MBTL1LMNAMAPTALDH1A1 | |
| SCHEMBL9805921 | 0.73 | SGMS2 (0.57) | SGMS2L3MBTL1LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |