Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.51 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725852 | 0.82 | DGKA (0.61) | DGKADNM1MAPTLMNAALDH1A1 | |
| SCHEMBL28711402 | 0.82 | NAAA (0.61) | DGKADNM1MAPTNAAAHTR2C | |
| SCHEMBL1905259 | 0.80 | NAAA (0.58) | DGKADNM1MAPTALDH1A1NAAA | |
| SCHEMBL9315300 | 0.78 | DGKA (0.57) | DGKADNM1MAPTLMNAALDH1A1 | |
| SCHEMBL31467774 | 0.77 | DGKA (0.69) | DGKADNM1MAPTLMNAALDH1A1 | |
| SCHEMBL28425931 | 0.77 | ALDH1A1 (0.53) | DGKAMAPTALDH1A1NAAATSHR | |
| SCHEMBL19896365 | 0.77 | ALDH1A1 (0.53) | DGKAMAPTALDH1A1NAAATSHR | |
| SCHEMBL22579030 | 0.77 | DGKA (0.69) | DGKADNM1MAPTLMNAALDH1A1 | |
| SCHEMBL28407493 | 0.76 | LMNA (0.38) | DNM1LMNATSHR | |
| SCHEMBL19896423 | 0.75 | ALDH1A1 (0.55) | DGKALMNAALDH1A1NAAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817632-A | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules | SYNZYME TECHNOLOGIES, INC. | 1998-10-06 | — | — | US | disclosed |