Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 5/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723548 | 0.71 | ADRA2B (0.84) | ADRA1AADRA2AADRA2BADRA2CPDPK1 | |
| SCHEMBL10930958 | 0.68 | CYP2D6 (0.83) | ADRA1AADRA2ACYP2D6HTR1AOPRM1 | |
| SCHEMBL11407636 | 0.68 | HTR2A (0.38) | ADRA1AADRA2AADRA2BADRA2CMEN1 | |
| SCHEMBL503849 | 0.67 | SIGMAR1 (0.62) | ADRA1ACYP2D6MEN1KMT2ATAAR1 | |
| SCHEMBL29390302 | 0.67 | SIGMAR1 (0.62) | ADRA1ACYP2D6MEN1KMT2ATAAR1 | |
| SCHEMBL8086470 | 0.67 | ADRA1A (0.63) | ADRA1AADRA2AADRA2BADRA2CCYP2D6 | |
| SCHEMBL30606845 | 0.66 | SIGMAR1 (0.60) | ADRA1ACYP2D6MEN1KMT2ATAAR1 | |
| SCHEMBL14247675 | 0.66 | ADRA1A (0.49) | ADRA1AADRA2ACYP2D6HTR1AOPRM1 | |
| SCHEMBL28806293 | 0.66 | ADRA1A (0.49) | ADRA1AADRA2ACYP2D6HTR1AOPRM1 | |
| Ammonia Solution, Strong SCHEMBL8210515 | 0.66 | SIGMAR1 (0.60) | ADRA1ACYP2D6MEN1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280085-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| EP-2048951-A2 | CHEMICAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008017816-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280085-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, COX6B1 | ADRA1A 1702/4885ADRA2A 2634/4885ADRA2B 2755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.