Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418865 | 0.88 | MEN1 (0.50) | ELANEALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9417828 | 0.86 | NPC1 (0.49) | ELANEALDH1A1KDM4EPTGER1PTGER4 | |
| SCHEMBL10664626 | 0.84 | MAOB (0.57) | MRGPRX4MAOBELANEALDH1A1SMN1; SMN2 | |
| SCHEMBL8675320 | 0.83 | MRGPRX4 (0.54) | MRGPRX4MAOBALDH1A1PTGER1PTGER4 | |
| SCHEMBL21483708 | 0.83 | MAOB (0.56) | MRGPRX4MAOBALDH1A1KDM4EPTGER1 | |
| SCHEMBL11179076 | 0.83 | MAOB (0.56) | MRGPRX4MAOBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9525514 | 0.82 | KDM4E (0.50) | ELANEALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL15338464 | 0.82 | MAOB (0.55) | MRGPRX4MAOBPTGER1PTGER4PTGER3 | |
| SCHEMBL21483714 | 0.82 | ALDH1A1 (0.55) | MRGPRX4MAOBALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3123036 | 0.81 | MAOB (0.64) | MRGPRX4MAOBALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |