SCHEMBL8675596

SCHEMBL8675596

CCC(NC(=O)C(C)C)c1ccc(C)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
LMNA P02545 2/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
CNR2 P34972 2/20 0.46
GPR139 Q6DWJ6 1/20 0.43
KCNA5 P22460 2/20 0.43
HPGD P15428 2/20 0.42
KDM4E B2RXH2 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ACHE P22303 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14521519 0.84 ALDH1A1 (0.58) ALDH1A1LMNAMEN1KMT2AKCNA5
SCHEMBL13302598 0.84 ALDH1A1 (0.58) ALDH1A1LMNAMEN1KMT2AKCNA5
SCHEMBL185572 0.82 ALDH1A1 (0.68) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL24315664 0.81 ROCK2 (0.45) ALDH1A1LMNASMN1; SMN2CNR2HPGD
SCHEMBL14521516 0.78 ACACB (0.49) LMNAMEN1KMT2ACNR2GPR139
SCHEMBL13075027 0.74 SMN1; SMN2 (0.51) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL14438298 0.74 SMN1; SMN2 (0.51) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL14338366 0.73 HDAC4 (0.49) ALDH1A1CNR2GPR139
SCHEMBL27010571 0.73 ADORA2B (0.49) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL14338398 0.73 TAS1R3 (0.52) ALDH1A1MEN1KMT2AGPR139HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5776976-A Fungicidal active compound combinations BAYER AKTIENGESELLSCHAFT (DE) 1998-07-07 US disclosed