Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 7/20 | 0.48 |
| ▸ | GCK | P35557 | 4/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326786 | 0.91 | PTGER1 (0.42) | PTGER1PTGER4PTGER3PTGER2SLC6A9 | |
| SCHEMBL8675115 | 0.82 | GCK (0.63) | PTGER1GCKPTGER4PTGER3PTGER2 | |
| SCHEMBL8676069 | 0.82 | PTGER1 (0.63) | PTGER1GCKPTGER4PTGER3PTGER2 | |
| SCHEMBL8676600 | 0.77 | PTGER1 (0.48) | PTGER1PTGER4PTGER3PTGER2SLC6A9 | |
| SCHEMBL8675829 | 0.76 | PTGER1 (0.71) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL8324992 | 0.76 | CCR5 (0.48) | PTGER1 | |
| SCHEMBL8327493 | 0.76 | MAPT (0.54) | PTGER1PTGER4PTGER3PTGER2SLC6A9 | |
| SCHEMBL8406036 | 0.74 | PTGER1 (0.47) | PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8325607 | 0.74 | PTGER1 (0.52) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL8327306 | 0.74 | GCK (0.53) | PTGER1GCKPTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |