Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 3/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675468 | 0.84 | MRGPRX4 (0.47) | SLC6A2SLC6A3KMT2ATDP1HDAC8 | |
| SCHEMBL8327587 | 0.80 | RXRA (0.49) | KMT2ALMNAUSP2PTGER1PTGER4 | |
| SCHEMBL8327584 | 0.80 | RXRA (0.49) | KMT2ALMNAUSP2PTGER1PTGER4 | |
| SCHEMBL8675824 | 0.76 | PTGER1 (0.48) | LMNAUSP2HDAC8PTGER1PTGER4 | |
| SCHEMBL8677984 | 0.75 | KMT2A (0.49) | SLC6A2SLC6A3KMT2ATDP1LMNA | |
| SCHEMBL15056730 | 0.75 | CCR5 (0.48) | KMT2ALMNAUSP2HDAC8PTGER1 | |
| SCHEMBL15056732 | 0.75 | CCR5 (0.48) | KMT2ALMNAUSP2HDAC8PTGER1 | |
| SCHEMBL4427861 | 0.75 | CCR5 (0.50) | LMNAUSP2PTGER1CCR5CCNB2 | |
| SCHEMBL849174 | 0.74 | LMNA (0.48) | SLC6A2SLC6A3KMT2ATDP1LMNA | |
| SCHEMBL849175 | 0.74 | LMNA (0.48) | SLC6A2SLC6A3KMT2ATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |