Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 10/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.42 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675455 | 0.88 | ESR1 (0.52) | TDP1SLC6A2SLC6A3KMT2APTGER1 | |
| SCHEMBL8676387 | 0.85 | PTGER1 (0.62) | TDP1SLC6A2SLC6A3KMT2APTGER1 | |
| SCHEMBL8676634 | 0.84 | MTNR1B (0.57) | TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL8676445 | 0.83 | MRGPRX4 (0.47) | TDP1SLC6A2SLC6A3KMT2APTGER1 | |
| SCHEMBL8675525 | 0.82 | PTGER1 (0.61) | TDP1SLC6A2SLC6A3KMT2APTGER1 | |
| SCHEMBL8677127 | 0.81 | RAB9A (0.56) | KMT2A | |
| SCHEMBL8676066 | 0.81 | ESR1 (0.52) | TDP1SLC6A2SLC6A3KMT2APTGER1 | |
| SCHEMBL8319623 | 0.80 | PTGER1 (0.73) | PTGER1PTGER4PTGER3PTGER2CYP1A2 | |
| SCHEMBL8675086 | 0.80 | TDP1 (0.55) | TDP1SLC6A2SLC6A3KMT2APTGER1 | |
| SCHEMBL14552394 | 0.80 | TDP1 (0.46) | TDP1SLC6A2SLC6A3KMT2APTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |