Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676066 | 0.90 | ESR1 (0.52) | ESR1ESR2TDP1LMNASLC6A2 | |
| SCHEMBL8675900 | 0.88 | TDP1 (0.48) | ESR1ESR2TDP1SLC6A2SLC6A3 | |
| SCHEMBL8676387 | 0.87 | PTGER1 (0.62) | ESR1ESR2TDP1LMNASLC6A2 | |
| SCHEMBL8676634 | 0.86 | MTNR1B (0.57) | TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL8676445 | 0.85 | MRGPRX4 (0.47) | ESR1ESR2TDP1SLC6A2SLC6A3 | |
| SCHEMBL8675525 | 0.84 | PTGER1 (0.61) | ESR1ESR2TDP1SLC6A2SLC6A3 | |
| SCHEMBL8677127 | 0.83 | RAB9A (0.56) | KMT2A | |
| SCHEMBL8675086 | 0.82 | TDP1 (0.55) | ESR1ESR2TDP1LMNASLC6A2 | |
| SCHEMBL14552394 | 0.81 | TDP1 (0.46) | ESR1ESR2TDP1SLC6A2SLC6A3 | |
| SCHEMBL8677652 | 0.81 | PTGER1 (0.49) | ESR1ESR2TDP1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |